abstract：:Gamma-glutamyltransferase (GGT) is a membrane-bound enzyme involved in the glutathione metabolism. Studies suggested that GGT was a marker of apoptotic balance and modulated tumor progression, invasion and drug resistance. Recently, GGT was shown to be associated with the progression of high-grade esophageal epithelia...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Yang F,Zhang S,Yang H,Luo K,Wen J,Hu Y,Hu R,Huang Q,Chen J,Fu J

更新日期：2015-07-01 00:00:00

abstract：:An association between gastroesophageal reflux disease (GERD) and diabetes mellitus (DM) has been reported. Studies have not been population-based and have failed to include a representative sample of African American subjects. The aim of the study was to determine if DM is independently associated with GERD among urb...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Natalini J,Palit A,Sankineni A,Friedenberg FK

更新日期：2015-07-01 00:00:00

abstract：:Human epidermal growth factor receptor 2 (HER2) is involved in the malignant progression of several human cancers, including esophageal adenocarcinoma (EAC). The purpose of this study was to evaluate HER2 overexpression and to explore the feasibility of confocal laser endomicroscopy for in vivo molecular imaging of HE...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Realdon S,Dassie E,Fassan M,Dall'Olmo L,Hatem G,Buda A,Arcidiacono D,Diamantis G,Zhang H,Greene MI,Sturniolo GC,Rugge M,Alberti A,Battaglia G

更新日期：2015-05-01 00:00:00

abstract：:Accurate evaluation of radical radiotherapy requires well designed research with valid and appropriate outcomes. This study reviewed standards of outcome reporting and study design in randomized controlled trials (RCTs) of radiation-based therapy for esophageal cancer and made recommendations for future work. Randomiz...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Main BG,Strong S,McNair AG,Falk SJ,Crosby T,Blazeby JM

更新日期：2015-02-01 00:00:00

abstract：:The mu-opioid receptor (MOR), a membrane-bound G protein-coupled receptor, is the main target for opioids in the nervous system. MOR1 has been found in several types of cancer cells and reported to be involved in tumor progression and metastasis. However, the expression and clinical significance of MOR1 in esophageal ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Zhang YF,Xu QX,Liao LD,Xu XE,Wu JY,Wu ZY,Shen JH,Li EM,Xu LY

更新日期：2015-02-01 00:00:00

abstract：:Human esophageal adenocarcinoma (EAC) cell lines have made a substantial contribution to elucidating mechanisms of carcinogenesis and drug discovery. Model research on EAC relies almost entirely on a relatively small set of established tumor cell lines because appropriate animal models are lacking. Nowadays, more than...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Boonstra JJ,Tilanus HW,Dinjens WN

更新日期：2015-01-01 00:00:00

abstract：:Apolipoprotein E (ApoE) is the most well-described genetic risk factor for Alzheimer's disease and nonpathological cognitive decline. While possession of the E2 allele may have protective properties, substantial research evidence suggests the E4 allele increases the risk of cognitive degeneration. As neurodegenerative...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Mentz H,Horan M,Payton A,Ollier W,Pendleton N,Hamdy S

更新日期：2015-01-01 00:00:00

abstract：:The objective of the study was to compare geometrical differences of target volumes based on four-dimensional computed tomography (4DCT) maximum intensity projection (MIP) and 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) images of primary thoracic esophageal cancer for radia...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Guo Y,Li J,Wang W,Zhang Y,Wang J,Duan Y,Shang D,Fu Z

更新日期：2014-11-01 00:00:00

abstract：:Identify prognostic factors for survival and patterns of treatment failure after definitive radiochemotherapy for esophageal cancer. Between 2003 and 2006, 143 patients with squamous cell carcinoma and adenocarcinoma of the esophagus were retrospectively reviewed. Median age was 65 years (42-81). Median radiation dose...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Clavier JB,Antoni D,Atlani D,Ben Abdelghani M,Schumacher C,Dufour P,Kurtz JE,Noel G

更新日期：2014-08-01 00:00:00

abstract：:It is well accepted that recurrent laryngeal nerve paralysis is a severe complication of esophagectomy or lymphadenectomy performed adjacent to the recurrent laryngeal nerves. Herein, determination of the effectiveness of implementing continuous recurrent laryngeal nerve monitoring to reduce the incidence of recurrent...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Zhong D,Zhou Y,Li Y,Wang Y,Zhou W,Cheng Q,Chen L,Zhao J,Li X,Yan X

更新日期：2014-07-01 00:00:00

abstract：:This study investigated whether the complaint of night-time heartburn (NHB) as opposed to daytime heartburn (DHB) is a reliable reflection of actual sleep-related reflux events. Three groups of individuals were studied: individuals with complaints of NHB at least twice per week (n = 24), individuals with complaints of...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Orr WC,Goodrich S,Estep ME,Shepherd K

更新日期：2014-05-01 00:00:00

abstract：:Endoscopic therapy (ablation +/- endoscopic resection) for high-grade dysplasia and/or intramucosal carcinoma (IMC) of the esophagus has demonstrated promising results. However, there is a concern that a curable, local disease may progress to systemic disease with repeated endotherapy. We performed a retrospective rev...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Hunt BM,Louie BE,Dunst CM,Lipham JC,Farivar AS,Sharata A,Aye RW

更新日期：2014-05-01 00:00:00

abstract：:Esophageal intramural pseudodiverticulosis is a rare disease that may lead to esophageal stenosis and dysphagia. The aim of the study was to evaluate the endoscopic diagnosis, treatment and clinical course of intramural pseudodiverticulosis. We retrospectively studied endoscopic criteria of intramural pseudodiverticul...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Halm U,Lamberts R,Knigge I,Mössner J,Zachäus M

更新日期：2014-04-01 00:00:00

abstract：:This study looks at toxicity and survival data when chemoradiation (CRT) is delivered using intensity-modulated radiation therapy (IMRT) after induction chemotherapy. Forty-one patients with esophageal adenocarcinoma treated with IMRT from March 2007 to May 2009 at Memorial Sloan-Kettering Cancer Center were analyzed....

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Gerber N,Ilson DH,Wu AJ,Janjigian YY,Kelsen DP,Zheng J,Zhang Z,Bains MS,Rizk N,Rusch VW,Goodman KA

更新日期：2014-04-01 00:00:00

abstract：:Interferon (IFN)-β has efficient antitumor effect both in vitro and in vivo, but its clinical implication is limited by short half-life and systemic toxicities. Gene therapy could be the choice to avoid the defects. Adenovirus vector containing human IFN-β gene was transfected into esophageal squamous cell carcinoma K...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Qi M,Lu D,Li Y,Qin J,Wang H,Zhang Z,Chen X,Duan F,Ma J

更新日期：2014-02-01 00:00:00

abstract：:Local failure after definitive chemoradiotherapy (CRT) for stage IB, II, and III esophageal cancer is one of the causes of poor outcome. Endoscopic mucosal resection (EMR) is an effective treatment for superficial esophageal cancer. However, its feasibility as a salvage treatment for local recurrent or residual tumors...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Makazu M,Kato K,Takisawa H,Yoshinaga S,Oda I,Saito Y,Mayahara H,Ito Y,Itami J,Hamaguchi T,Yamada Y,Shimada Y

更新日期：2014-01-01 00:00:00

abstract：:The high-resolution microendoscope (HRME) is a novel imaging modality that may be useful in the surveillance of Barrett's esophagus in low-resource or community-based settings. In order to assess accuracy and interrater reliability of microendoscopists in identifying Barrett's-associated neoplasia using HRME images, w...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Vila PM,Kingsley MJ,Polydorides AD,Protano MA,Pierce MC,Sauk J,Kim MK,Patel K,Godbold JH,Waye JD,Richards-Kortum R,Anandasabapathy S

更新日期：2014-01-01 00:00:00

abstract：:One-lung ventilation (OLV) is applied during esophagectomy to improve exposure during the thoracic part of the operation. Collapse of lung tissue, shunting of pulmonary blood flow, and changes in alveolar oxygenation during and after OLV may possibly induce an ischemia-reperfusion response in the lung, which may affec...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Lund M,Ny L,Malmström RE,Lundberg JO,Öst Å,Björnstedt M,Lundell L,Tsai JA

更新日期：2013-11-01 00:00:00

abstract：:Prevalence data for heartburn in the urban Black American community is lacking. In order to estimate prevalence for this community, we analyzed data from an ongoing cohort study in progress at our hospital. Comprehensive interviews allowed for exploration of factors associated with heartburn. Complex, stratified sampl...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Friedenberg FK,Makipour K,Palit A,Shah S,Vanar V,Richter JE

更新日期：2013-08-01 00:00:00

abstract：:Barrett's esophagus (BE) is the strongest risk factor for the development of esophageal adenocarcinoma. However, the risk of cancer progression is difficult to ascertain in individuals, as a significant number of patients with BE do not necessarily progress to esophageal adenocarcinoma. There are several issues with t...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Timmer MR,Sun G,Gorospe EC,Leggett CL,Lutzke L,Krishnadath KK,Wang KK

更新日期：2013-08-01 00:00:00

abstract：:Until now, it is uncertain if the so-called pH-only reflux episodes that consist of a pH drop without evidence of retrograde bolus movement in multichannel intraluminal impedance (MII) represent reflux episodes or artifacts. Hiatal hernia (HH) may allow reflux of small volumes to occur that can be detected by pH-metry...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Weigt J,Malfertheiner P

更新日期：2013-07-01 00:00:00

abstract：:The prevalence of gastroesophageal reflux disease (GERD) has increased recently in Asia-Pacific countries. However, little is known about its prevalence and clinical characteristics in GERD patients with atypical symptoms in Asia. The aim of this study was to investigate the clinical characteristics of GERD in patient...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Oh JH,Choi MG,Park JM,Lim CH,Cho YK,Lee IS,Kim SW,Chung IS

更新日期：2013-07-01 00:00:00

abstract：:The progression of certain primary esophageal motor disorders to achalasia has been documented; however, the true incidence of this decay is still elusive. This study aims to evaluate: (i) the incidence of the progression of diffuse esophageal spasm to achalasia, and (ii) predictive factors to this progression. Thirty...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Fontes LH,Herbella FA,Rodriguez TN,Trivino T,Farah JF

更新日期：2013-07-01 00:00:00

abstract：:Esophageal atresia (EA) occurs in one out of 2500 to 4500 live births. As the vast majority of infants are now surviving neonatal corrective surgery, the focus has shifted from mortality to morbidity associated with EA. However, little is known about its psychological morbidity. This paper synthesizes research and cli...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Caplan A

更新日期：2013-05-01 00:00:00

abstract：:Patients with Barrett's esophagus are at risk for dysplasia and esophageal adenocarcinoma. Although surgery was the mainstay treatment for Barrett's dysplasia and cancer, patients with high-grade dysplasia and early cancers now have several nonsurgical treatment options. Most of the endoscopic therapies are relatively...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Allende D,Dumot J,Yerian L

更新日期：2013-04-01 00:00:00

abstract：:Benign esophagorespiratory fistula is a relatively rare condition in adults that poses a technical challenge to manage. This case series describes our experience in the treatment of benign esophagorespiratory fistula in 12 adults. A retrospective review of case records of 12 patients with benign esophagorespiratory fi...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Deshpande G,Samarasam I,Banerjee S,Gnanamuthu RB,Chandran S,Mathew G

更新日期：2013-02-01 00:00:00

abstract：:Carcinoma of the esophagus is classified according to the Union for International Cancer Control (UICC) TNM staging system. The 7th edition of the UICC TNM staging system was published in 2009. This is the first study to compare the prognostic value of the TNM 6th and 7th editions in patients with esophageal carcinoma...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Mehta SP,Jose P,Mirza A,Pritchard SA,Hayden JD,Grabsch HI

更新日期：2013-02-01 00:00:00

abstract：:The involvement of S100A4 in modulating invasiveness of esophageal squamous cell carcinoma (ESCC) cell lines was explored. It was shown that S100A4 expression is positively correlated with the degree of invasiveness in human ESCC cells. The S100A4-rich EC-1 cells displayed higher migratory and invasive cell behavior w...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Zhang K,Zhang M,Zhao H,Yan B,Zhang D,Liang J

更新日期：2012-11-01 00:00:00

abstract：:Gastro-tracheobronchial fistula (GTF) is a rare but life-threatening complication specifically observed after esophagectomy and reconstruction using posterior mediastinal gastric tube. Ten cases of GTF were encountered in three hospitals in 2000-2009. Their clinicopathological, surgical, and postoperative care are sum...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Yasuda T,Sugimura K,Yamasaki M,Miyata H,Motoori M,Yano M,Shiozaki H,Mori M,Doki Y

更新日期：2012-11-01 00:00:00

abstract：:We examined the value of impedance monitoring in measuring bolus volume compared with videoesophagram. Eighty consecutive subjects were studied with simultaneous impedance-manometry-videoesophagram. A catheter with both an impedance electrode pair and a pressure transducer at four sites (5, 10, 15, 20 cm above lower e...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Imam H,Marrero F,Shay S

更新日期：2012-09-01 00:00:00

abstract：:High body mass index (H-BMI; ≥25 kg/m(2) ) is common in US adults. In a small cohort of esophageal cancer (EC) patients treated with surgery, H-BMI and diagnosis of early stage EC appeared associated. We evaluated a much larger cohort of EC patients. From a prospectively maintained database, we analyzed 925 EC patient...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Hayashi Y,Correa AM,Hofstetter WL,Vaporciyan AA,Mehran RJ,Rice DC,Suzuki A,Lee JH,Bhutani MS,Welsh J,Lin SH,Maru DM,Swisher SG,Ajani JA

更新日期：2012-09-01 00:00:00

abstract：:While diagnostic overlap exists between gastroesophageal reflux disease and eosinophilic esophagitis especially on histological findings, therapeutic approaches for the two disease entities are very different. Recently, anti-inflammatory treatment, in addition to acid suppressants, has been investigated for gastroesop...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Lee H,Park JC,Shin SK,Lee SK,Lee YC

更新日期：2012-09-01 00:00:00

abstract：:According to the Montreal Consensus Group's classification, gastroesophageal reflux disease develops when the reflux of stomach contents causes troublesome symptoms and/or complications such as esophagitis. The characteristic gastroesophageal reflux disease symptoms included in this statement are retrosternal burning ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Sawaya RA,Macgill A,Parkman HP,Friedenberg FK

更新日期：2012-08-01 00:00:00

abstract：:There are limited data concerning the effects of 5-HT(1A) receptor activation on esophageal motility. Sumatriptan, a 5-HT(1A) receptor agonist, was recently reported to enhance esophageal peristalsis after intravenous administration. Buspirone, an orally available 5-HT(1A) receptor agonist, was shown to modulate gastr...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Di Stefano M,Papathanasopoulos A,Blondeau K,Vos R,Boecxstaens V,Farré R,Rommel N,Tack J

更新日期：2012-07-01 00:00:00

abstract：:Diagnosis of esophageal atresia (EA) with tracheo-esophageal fistula (TEF) can be easily done in newborns with symptoms of excessive salivation and failure to pass infant-feeding tube (IFT) into the stomach. There are many reports in the literature which describe the diagnostic pitfall of this IFT test. We describe a ...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Rathod K,Khanna S,Kanojia RP,Rao KL

更新日期：2012-07-01 00:00:00

abstract：:Despite symptom improvement offered to achalasia patients by either pneumatic dilation or surgical myotomy, 10% to 15% of those so treated will present progressive deterioration of their esophageal function and up to 5% may eventually require an esophagectomy. The natural evolution of achalasia to its end stage as wel...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Duranceau A,Liberman M,Martin J,Ferraro P

更新日期：2012-05-01 00:00:00

abstract：:Hiatal hernia is an underlying factor contributing to gastroesophageal reflux disease (GERD). However, it remains elusive whether the size of the esophageal hiatus has a de facto influence on the lower esophageal sphincter (LES), on the intensity of patient reflux, on GERD symptoms and on the quality of life (QoL). On...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Koch OO,Kaindlstorfer A,Antoniou SA,Asche KU,Granderath FA,Pointner R

更新日期：2012-04-01 00:00:00

abstract：:Noncardiac chest pain (NCCP) is a common and challenging clinical problem. It is estimated that more than 70 million Americans (23% of the population) suffer from this condition yearly. Patients with NCCP represent a diagnostic dilemma. Their chest pain is often indistinguishable from cardiac pain leading to extensive...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Fass R,Achem SR

更新日期：2012-02-01 00:00:00

abstract：:Para-aortic lymph node (PALN) recurrence is often seen in patients with lower thoracic esophageal cancer treated by esophagectomy with extended lymph node dissection. However, the clinicopathological characteristics of patients with PALN metastasis and the significance of PALN dissection are unknown. A total of 283 pa...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Tanaka K,Yano M,Motoori M,Doki Y,Kishi K,Miyashiro I,Shingai T,Gotoh K,Noura S,Takahashi H,Ohue M,Yamada T,Ohigashi H,Ishikawa O

更新日期：2012-02-01 00:00:00

abstract：:Animal models of Barrett's metaplasia and esophageal adenocarcinoma are important to further characterize the disease and test potential therapies. This paper reviews the development of the surgical model of esophageal adenocarcinoma in the rat and considers whether this model provides a biologically accurate represen...

journal_title：Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus

authors： Hindmarsh A,Belshaw N,Mehta S,Johnson IT,Rhodes M

更新日期：2012-02-01 00:00:00